SCHEMBL28588342

SCHEMBL28588342

[c]1csc2cccc(-c3ccncc3)c12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.37
MAPT P10636 4/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
KDM4E B2RXH2 2/20 0.34
GFER P55789 1/20 0.34
NOTUM Q6P988 1/20 0.33
LMNA P02545 1/20 0.33
MAPK14 Q16539 2/20 0.33
CYP17A1 P05093 2/20 0.32
CYP1A2 P05177 1/20 0.32
PRKCI P41743 1/20 0.32
ALDH1A1 P00352 3/20 0.31
IMPDH2 P12268 2/20 0.31
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.31
HSD17B10 Q99714 2/20 0.31
NAMPT P43490 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21879640 0.82 CYP2A6 (0.44) MAPTNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL21295804 0.76 RAB9A (0.38) PIK3CDMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL28571384 0.73 KDM4E (0.41) MAPTNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL21295598 0.72 PIK3CD (0.37) PIK3CDMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL28570827 0.68 KDM4E (0.34) PIK3CDMAPTNPC1RAB9AKDM4E
SCHEMBL2207004 0.66 SMN1; SMN2 (0.33) MAPTNPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL4462961 0.66 LMNA (0.33) MAPTLMNACYP1A2ALDH1A1TSHR
SCHEMBL26259561 0.66 PIK3CD (0.61) PIK3CDMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL16150637 0.66 NOTUM (0.38) PIK3CDMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL21295808 0.66 PIK3CD (0.44) PIK3CDMAPTNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed