Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 4/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22075118 | 0.85 | FFAR1 (0.46) | FFAR1DGAT1F11F2PRSS1 | |
| SCHEMBL18979268 | 0.80 | FFAR1 (0.40) | FFAR1DGAT1UCHL1 | |
| SCHEMBL28410412 | 0.78 | FFAR1 (0.48) | FFAR1DGAT1 | |
| SCHEMBL28410414 | 0.78 | FFAR1 (0.48) | FFAR1DGAT1 | |
| SCHEMBL2543013 | 0.77 | FFAR1 (0.48) | FFAR1DGAT1F11F2PRSS1 | |
| SCHEMBL28588609 | 0.76 | FFAR1 (0.57) | FFAR1DGAT1F11F2PRSS1 | |
| SCHEMBL837310 | 0.75 | FFAR1 (0.51) | FFAR1DGAT1F11F2PRSS1 | |
| SCHEMBL18895313 | 0.74 | FFAR1 (0.47) | FFAR1DGAT1F11F2PRSS1 | |
| SCHEMBL17801161 | 0.74 | FFAR1 (0.48) | FFAR1DGAT1F11F2PRSS1 | |
| SCHEMBL17815975 | 0.74 | FFAR1 (0.48) | FFAR1DGAT1AAK1UCHL1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728941-A | Substituted 1, 5-naphthyridines or quinolines as ALK5 inhibitors | 施万生物制药研发IP有限责任公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-105777776-B | Inhibitors of protein tyrosine kinase activity | 梅特希尔基因公司 | 2021-06-08 | — | — | CN | disclosed |