Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837310 | 0.86 | FFAR1 (0.51) | FFAR1DGAT1USP30AAK1F2 | |
| SCHEMBL3663499 | 0.84 | FFAR1 (0.45) | FFAR1DGAT1USP30UCHL1AAK1 | |
| SCHEMBL17815873 | 0.81 | FFAR1 (0.45) | FFAR1DGAT1UCHL1AAK1HIF1A | |
| SCHEMBL17801161 | 0.78 | FFAR1 (0.48) | FFAR1DGAT1USP30UCHL1AAK1 | |
| SCHEMBL23303904 | 0.78 | KMT2A (0.41) | FFAR1DGAT1UCHL1F2F11 | |
| SCHEMBL28588606 | 0.77 | FFAR1 (0.47) | FFAR1DGAT1USP30UCHL1AAK1 | |
| SCHEMBL31489444 | 0.76 | LPL (0.39) | FFAR1DGAT1UCHL1F2F11 | |
| SCHEMBL17815975 | 0.75 | FFAR1 (0.48) | FFAR1DGAT1USP30UCHL1AAK1 | |
| SCHEMBL23389866 | 0.75 | FFAR1 (0.46) | FFAR1DGAT1USP30UCHL1AAK1 | |
| SCHEMBL18530443 | 0.75 | FFAR1 (0.44) | FFAR1DGAT1USP30UCHL1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379523-A1 | 4, 6-DISUBSTITUTED 2-AMINO-PYRIMIDINES AS HISTAMINE H4 RECEPTOR MODULATORS | Incyte Corporation (US) | 2011-10-26 | — | — | EP | disclosed |