Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 11/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28583441 | 0.88 | XDH (0.71) | XDHFFAR1ALKBH1CYP4F2CYP4A11 | |
| SCHEMBL28574824 | 0.88 | XDH (0.54) | XDHFFAR1ALKBH1CYP4F2CYP4A11 | |
| SCHEMBL28588699 | 0.88 | XDH (0.54) | XDHFFAR1ALKBH1CYP4F2CYP4A11 | |
| SCHEMBL28587001 | 0.81 | XDH (0.56) | XDHFFAR1ALKBH1ADAMTS4MMP13 | |
| SCHEMBL28588707 | 0.80 | XDH (0.63) | XDHFFAR1CYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL28583439 | 0.78 | XDH (0.61) | XDHFFAR1ALKBH1CYP4F2CYP4A11 | |
| SCHEMBL28568631 | 0.76 | XDH (0.63) | XDHCYP4F2CYP4A11MRGPRX4MCL1 | |
| SCHEMBL28572338 | 0.76 | XDH (0.63) | XDHCYP4F2CYP4A11MRGPRX4MCL1 | |
| SCHEMBL28582833 | 0.76 | XDH (0.63) | XDHCYP4F2CYP4A11MRGPRX4MCL1 | |
| SCHEMBL28574650 | 0.72 | XDH (0.52) | XDHCYP4F2CYP4A11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979559-A | 2-phenyl pyrimidine formic acid derivative and preparation method and application thereof | 沈阳药科大学 | 2021-06-18 | — | — | CN | claimed |
| CN-112979559-A | 2-phenyl pyrimidine formic acid derivative and preparation method and application thereof | 沈阳药科大学 | 2021-06-18 | — | — | CN | disclosed |