SCHEMBL2858902

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2864250	0.88	KDM4E (0.38)	ADORA2AFYNKDM4EKMT2AMAPT
	SCHEMBL2872658	0.86	ADORA2A (0.41)	ADORA2AKDM4EALDH1A1NPSR1LMNA
	SCHEMBL27536115	0.82	ALDH1A1 (0.41)	KDM4EALDH1A1NPSR1LMNAPOLB
	SCHEMBL2860001	0.80	ADORA2A (0.42)	ADORA2AKDM4EALDH1A1NPSR1LMNA
	SCHEMBL2861498	0.79	FYN (0.36)	ADORA2AFYNADORA2BADORA1DPP4
	SCHEMBL2857932	0.76	PTGER1 (0.41)	KMT2AMAPTMEN1ALDH1A1POLB
	SCHEMBL2867613	0.75	ADORA2A (0.39)	ADORA2AKDM4EALDH1A1HTTADORA2B
	SCHEMBL2870394	0.74	PTGER1 (0.43)	ADORA2AKDM4EALDH1A1NPSR1LMNA
	SCHEMBL4139399	0.73	CSNK2A2 (0.41)	ADORA2AFYNKDM4EALDH1A1NPSR1
	SCHEMBL4136387	0.73	CSNK2A2 (0.41)	ADORA2AFYNKDM4EALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.