Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29516862 | 1.00 | POLB (0.64) | POLBNPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL1715521 | 0.80 | KDR (0.55) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL4324471 | 0.80 | NPC1 (0.51) | POLBNPC1RAB9AL3MBTL1PTGS2 | |
| SCHEMBL2902134 | 0.80 | SMN1; SMN2 (0.50) | POLBNPC1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL1714806 | 0.80 | KDR (0.58) | POLBNPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL1714828 | 0.79 | NPC1 (0.50) | POLBNPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL3579374 | 0.78 | POLB (1.00) | POLBRAB9AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL920392 | 0.78 | NSD2 (0.66) | POLBL3MBTL1LMNASMN1; SMN2GAA | |
| SCHEMBL24003686 | 0.77 | P2RX7 (0.64) | POLBNPC1LMNASMN1; SMN2GFER | |
| SCHEMBL1715758 | 0.76 | KDR (0.62) | LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004196-A | N- (benzyloxy) -2-chloronicotinamides compound and preparation method and application thereof | 浙江工业大学 | 2021-06-22 | — | — | CN | claimed |
| CN-113004196-B | N- (benzyloxy) -2-chloronicotinamides compound and preparation method and application thereof | 浙江工业大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-113004196-B | N- (benzyloxy) -2-chloronicotinamides compound and preparation method and application thereof | 浙江工业大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-113004196-B | N- (benzyloxy) -2-chloronicotinamides compound and preparation method and application thereof | 浙江工业大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-113004196-A | N- (benzyloxy) -2-chloronicotinamides compound and preparation method and application thereof | 浙江工业大学 | 2021-06-22 | — | — | CN | disclosed |
| CN-113004196-A | N- (benzyloxy) -2-chloronicotinamides compound and preparation method and application thereof | 浙江工业大学 | 2021-06-22 | — | — | CN | disclosed |
| CN-113004196-A | N- (benzyloxy) -2-chloronicotinamides compound and preparation method and application thereof | 浙江工业大学 | 2021-06-22 | — | — | CN | disclosed |