Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 4/20 | 0.40 |
| ▸ | F13A1 | P00488 | 3/20 | 0.40 |
| ▸ | TGM1 | P22735 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | AOC2 | O75106 | 8/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24025550 | 1.00 | TGM2 (0.40) | TGM2F13A1TGM1NAMPTAOC2 | |
| SCHEMBL24025513 | 0.93 | F13A1 (0.41) | TGM2F13A1TGM1NAMPTAOC2 | |
| SCHEMBL24025663 | 0.92 | F13A1 (0.40) | TGM2F13A1TGM1NAMPTAOC2 | |
| SCHEMBL24057972 | 0.89 | NAMPT (0.46) | TGM2F13A1TGM1NAMPTPTGDR | |
| SCHEMBL26284110 | 0.87 | PTGDR (0.40) | AOC2PTGDRMAOAMAOBKDM4E | |
| SCHEMBL23779149 | 0.86 | AOC2 (0.39) | TGM2F13A1TGM1NAMPTAOC2 | |
| SCHEMBL23779148 | 0.86 | AOC2 (0.39) | TGM2F13A1TGM1NAMPTAOC2 | |
| SCHEMBL23779145 | 0.85 | NAMPT (0.39) | TGM2F13A1TGM1NAMPTAOC2 | |
| SCHEMBL24057612 | 0.84 | AOC2 (0.48) | AOC2MAOAMAOB | |
| SCHEMBL24025442 | 0.84 | AOC2 (0.48) | AOC2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112955214-B | Pyridylsulfonamide derivatives, pharmaceutical compositions and uses thereof | 勃林格殷格翰国际有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-112955214-A | Pyridylsulfonamide derivatives, pharmaceutical compositions and uses thereof | 勃林格殷格翰国际有限公司 | 2021-06-11 | — | — | CN | disclosed |