Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 14/20 | 0.46 |
| ▸ | MTOR | P42345 | 11/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | BRD2 | P25440 | 2/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.36 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.35 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993047 | 0.85 | PIK3CA (0.56) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL9905396 | 0.84 | PIK3CA (0.46) | PIK3CAMTORBRD4BRD2BRD3 | |
| SCHEMBL31439330 | 0.81 | BRD4 (0.45) | PIK3CAMTORBRD4BRD2BRD3 | |
| SCHEMBL5653378 | 0.80 | PIK3CA (0.42) | PIK3CAMTORPIK3CDCHEK1AKT1 | |
| SCHEMBL20390762 | 0.79 | PIK3CA (0.44) | PIK3CAMTORBRD4BRD2BRD3 | |
| SCHEMBL31439381 | 0.79 | PIK3CA (0.44) | PIK3CAMTORBRD4BRD2BRD3 | |
| SCHEMBL31439387 | 0.75 | PIK3CA (0.41) | PIK3CAMTORPIK3CDCHEK1ATM | |
| SCHEMBL18998180 | 0.75 | GABRA1 (0.54) | BRD4BRD2BRD3CHEK1ATM | |
| SCHEMBL1074861 | 0.75 | KDM4E (0.46) | BRD4BRD2BRD3GABRA1GABRG2 | |
| SCHEMBL31439289 | 0.75 | PIK3CA (0.47) | PIK3CAMTORPIK3CDPIK3CGPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108752336-B | Imidazoquinoline derivatives and application thereof | 常州润诺生物科技有限公司 | 2021-06-04 | — | — | CN | disclosed |