Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 13/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21791249 | 0.88 | BTK (0.46) | BTKKCNH2BDKRB1 | |
| SCHEMBL21776789 | 0.87 | BTK (0.41) | BTKKCNH2MEN1KMT2APOLB | |
| SCHEMBL21776824 | 0.85 | BTK (0.47) | BTKKCNH2BDKRB1 | |
| SCHEMBL28590953 | 0.77 | KDM4C (0.40) | BTK | |
| SCHEMBL19878131 | 0.76 | BTK (0.67) | BTKKCNH2BDKRB1 | |
| SCHEMBL20683040 | 0.76 | BTK (0.45) | BTKBDKRB1 | |
| SCHEMBL29766552 | 0.76 | BTK (0.45) | BTKBDKRB1 | |
| SCHEMBL18179513 | 0.73 | AAK1 (0.43) | BTKBDKRB1 | |
| SCHEMBL17660340 | 0.73 | AKT1 (0.44) | BTKMEN1KMT2AMAPT | |
| SCHEMBL29918950 | 0.73 | AAK1 (0.43) | BTKBDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112930213-A | Fused imidazopyridines as reversible inhibitors of Bruton's Tyrosine Kinase (BTK) | 默克专利有限公司 | 2021-06-08 | — | — | CN | disclosed |