Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 9/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28578712 | 0.88 | KDM4C (0.43) | KDM4CBTKHTR6FFAR1 | |
| SCHEMBL21776789 | 0.81 | BTK (0.41) | BTK | |
| SCHEMBL28590955 | 0.77 | BTK (0.43) | BTK | |
| SCHEMBL21791249 | 0.64 | BTK (0.46) | BTK | |
| SCHEMBL28465829 | 0.64 | PPARD (0.48) | KDM4CFFAR1 | |
| SCHEMBL18131869 | 0.63 | ERN1 (0.46) | KDM4C | |
| SCHEMBL20067086 | 0.62 | ALDH1A1 (0.39) | — | |
| SCHEMBL17660339 | 0.62 | AKT1 (0.34) | — | |
| SCHEMBL21776824 | 0.61 | BTK (0.47) | BTK | |
| SCHEMBL17660343 | 0.61 | BTK (0.40) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112930213-A | Fused imidazopyridines as reversible inhibitors of Bruton's Tyrosine Kinase (BTK) | 默克专利有限公司 | 2021-06-08 | — | — | CN | disclosed |