SCHEMBL285919

SCHEMBL285919

CC(C)(C)c1cccc2c1ccc1c3ccccc3ccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.58
ALDH1A1 P00352 6/20 0.50
HSD17B10 Q99714 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
CYP2A6 P11509 2/20 0.50
TSHR P16473 2/20 0.50
PAX8 Q06710 1/20 0.43
CYP1A2 P05177 3/20 0.43
HPGD P15428 2/20 0.43
KIF11 P52732 1/20 0.43
HIF1A Q16665 1/20 0.43
CYP1B1 Q16678 1/20 0.43
THRB P10828 1/20 0.43
CA2 P00918 1/20 0.41
LMNA P02545 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
APEX1 P27695 1/20 0.40
MAPK1 P28482 1/20 0.40
PMP22 Q01453 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2015958 1.00 HPRT1 (0.58) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL29972825 0.87 KIF11 (0.48) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL252402 0.87 KIF11 (0.48) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL4818310 0.87 KIF11 (0.48) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL3779052 0.85 KIF11 (0.47) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL3779049 0.85 KIF11 (0.47) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL24422042 0.84 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
Formaldehyde SCHEMBL28441436 0.81 KIF11 (0.44) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL27605437 0.80 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL12310595 0.79 HPRT1 (0.58) HPRT1ALDH1A1HSD17B10TDP1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2427531-A1 DEUTERATED COMPOUNDS FOR LUMINESCENT APPLICATIONS E. I. du Pont de Nemours and Company (US) 2012-03-14 EP disclosed
EP-2376593-A2 PHOTOACTIVE COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION E. I. du Pont de Nemours and Company (US) 2011-10-19 EP disclosed
WO-2010128996-A1 DEUTERATED COMPOUNDS FOR LUMINESCENT APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-11-11 WO disclosed
WO-2010068865-A2 PHOTOACTIVE COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-17 WO disclosed
EP-2152662-A1 CHRYSENES FOR BLUE LUMINESCENT APPLICATIONS E. I. Du Pont de Nemours and Company (US) 2010-02-17 EP disclosed
WO-2008147721-A1 CHRYSENES FOR BLUE LUMINESCENT APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-04 WO disclosed