Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29972825 | 1.00 | KIF11 (0.48) | KIF11ALDH1A1CYP2A6CA2TSHR | |
| SCHEMBL252402 | 1.00 | KIF11 (0.48) | KIF11ALDH1A1CYP2A6CA2TSHR | |
| SCHEMBL3779052 | 0.98 | KIF11 (0.47) | KIF11ALDH1A1CYP2A6CA2TSHR | |
| SCHEMBL3779049 | 0.98 | KIF11 (0.47) | KIF11ALDH1A1CYP2A6CA2TSHR | |
| Formaldehyde SCHEMBL28441436 | 0.93 | KIF11 (0.44) | KIF11ALDH1A1CYP2A6CA2TSHR | |
| Formic Acid SCHEMBL27662627 | 0.88 | CA2 (0.43) | KIF11ALDH1A1CYP2A6CA2TSHR | |
| SCHEMBL285919 | 0.87 | HPRT1 (0.58) | KIF11ALDH1A1CYP2A6CA2TSHR | |
| SCHEMBL2015958 | 0.87 | HPRT1 (0.58) | KIF11ALDH1A1CYP2A6CA2TSHR | |
| SCHEMBL28297056 | 0.85 | ALDH1A1 (0.48) | KIF11ALDH1A1CYP2A6CA2TSHR | |
| Cyclobutanol SCHEMBL9815506 | 0.83 | CA2 (0.39) | KIF11ALDH1A1CA2TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358396-B2 | Preparation of optically active amines | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-15 | — | — | US | disclosed |
| US-20070155971-A1 | Chiral diphosphorus compounds and their transition metal complexes | Source Global, PBC | 2007-07-05 | — | — | US | disclosed |
| US-7193092-B2 | Chiral diphosphorus compounds and their transition metal complexes | LANXESS DEUTSCHLAND GMBH (DE) | 2007-03-20 | — | — | US | disclosed |
| US-7078226-B1 | Method for producing optically active amines | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-18 | — | — | US | disclosed |
| US-20060122429-A1 | Preparation of optically active amines | DITRICH KLAUS | 2006-06-08 | — | — | US | disclosed |
| EP-1400527-B1 | Chiral diphosphorus compounds and transition metal complexes thereof | LANXESS DEUTSCHLAND GMBH (DE) | 2006-03-22 | — | — | EP | disclosed |
| EP-1398319-B1 | Chiral monophosphorus compounds and transition metal complexes thereof | LANXESS DEUTSCHLAND GMBH (DE) | 2005-11-09 | — | — | EP | disclosed |
| US-20050080047-A1 | Chiral diphosphorus compounds and their transition metal complexes | LANXESS DEUTSCHLAND GMBH (DE) | 2005-04-14 | — | — | US | disclosed |
| EP-1232279-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | BASF AG (DE) | 2005-03-02 | — | — | EP | disclosed |
| US-20040127430-A1 | Chiral monophosphorus compounds and their transition metal complexes | LANXESS DEUTSCHLAND GMBH (DE) | 2004-07-01 | — | — | US | disclosed |
| EP-1400527-A1 | Chiral diphosphorus compounds and transition metal complexes thereof | Bayer Chemicals AG (DE) | 2004-03-24 | — | — | EP | disclosed |
| EP-1398319-A1 | Chiral monophosphorus compounds and transition metal complexes thereof | Bayer Chemicals AG (DE) | 2004-03-17 | — | — | EP | disclosed |
| EP-1232279-A2 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-08-21 | — | — | EP | disclosed |
| EP-0906324-B1 | CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS | BASF AG (DE) | 2001-08-01 | — | — | EP | disclosed |
| US-6242583-B1 | COUPLING CARBOHYDRATE COMPOUNDS IN PRESENCE OF PROMOTER TO A FUNCTIONALIZED SOLID SUPPORT | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-05 | — | — | US | disclosed |
| WO-2001038292-A2 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-31 | — | — | WO | disclosed |
| US-5990320-A | Optically active diphosphine ligands | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-23 | — | — | US | disclosed |
| EP-0906324-A1 | CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997045436-A1 | CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122429-A1 | Preparation of optically active amines | MAOA, MAOB, NAAA | KIF11 1540/4885ALDH1A1 283/4885CYP2A6 753/4885 |
| US-20040127430-A1 | Chiral monophosphorus compounds and their transition metal complexes | MDM4, MPHOSPH6, AP3M1 | KIF11 2512/4885ALDH1A1 4060/4885CYP2A6 1161/4885 |
| US-20070155971-A1 | Chiral diphosphorus compounds and their transition metal complexes | CDIPT, DCPS, PIN1 | KIF11 2079/4885ALDH1A1 3235/4885CYP2A6 701/4885 |
| US-20050080047-A1 | Chiral diphosphorus compounds and their transition metal complexes | CDIPT, DCPS, PIN1 | KIF11 2079/4885ALDH1A1 3235/4885CYP2A6 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.