Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851181 | 0.88 | CASP1 (0.55) | CASP1ALDH1A1MAPTCYP1A2GPR35 | |
| SCHEMBL2849381 | 0.86 | CASP1 (0.39) | CASP1KDM4EL3MBTL1CTSATDP1 | |
| SCHEMBL13500113 | 0.80 | CASP1 (0.54) | CASP1ALDH1A1MAPTXPO1GPR35 | |
| SCHEMBL2874441 | 0.79 | CASP1 (0.53) | CASP1ALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL2849135 | 0.76 | CASP1 (0.56) | CASP1ALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL2851268 | 0.75 | CASP1 (0.58) | CASP1ALDH1A1MAPTCYP1A2XPO1 | |
| SCHEMBL2851591 | 0.75 | CASP1 (0.39) | CASP1ALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL15918360 | 0.74 | CASP1 (0.71) | CASP1ALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL15917187 | 0.73 | CASP1 (1.00) | CASP1ALDH1A1MAPTGPR35KMT2A | |
| SCHEMBL30425504 | 0.73 | CASP1 (1.00) | CASP1ALDH1A1MAPTGPR35KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924558-B1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2010-01-13 | — | — | EP | claimed |