Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ECE1 | P42892 | 3/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851591 | 0.89 | CASP1 (0.39) | CASP1KDM4EL3MBTL1CTSAMAPK1 | |
| SCHEMBL2859246 | 0.86 | CASP1 (0.57) | CASP1KDM4EL3MBTL1CTSATDP1 | |
| SCHEMBL2851181 | 0.79 | CASP1 (0.55) | CASP1CTSATDP1 | |
| SCHEMBL13500047 | 0.78 | CASP1 (0.40) | CASP1 | |
| SCHEMBL2851215 | 0.75 | KDM4E (0.33) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL2851771 | 0.74 | CASP1 (0.39) | CASP1KDM4ECTSALMNA | |
| SCHEMBL15525179 | 0.74 | EGFR (0.45) | CASP1KDM4E | |
| SCHEMBL2850940 | 0.73 | CASP1 (0.43) | CASP1CTSALMNA | |
| SCHEMBL2851376 | 0.71 | SCN9A (0.34) | KDM4EL3MBTL1CTSAMAPK1TSHR | |
| SCHEMBL2853110 | 0.69 | CASP1 (0.44) | CASP1CTSATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924558-B1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2010-01-13 | — | — | EP | claimed |