Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | CD74 | P04233 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31300953 | 0.86 | KDM4E (0.57) | DHFRCD74MIFSMN1; SMN2KDM4E | |
| SCHEMBL17899331 | 0.85 | CCR1 (0.67) | CD74MIFSMN1; SMN2KDM4ELMNA | |
| SCHEMBL18904499 | 0.78 | CCR1 (0.44) | CD74MIFSMN1; SMN2KDM4ELMNA | |
| SCHEMBL12954936 | 0.78 | SMN1; SMN2 (0.47) | CD74MIFSMN1; SMN2KDM4ELMNA | |
| SCHEMBL18904500 | 0.77 | CD74 (0.42) | CD74MIFSMN1; SMN2KDM4ELMNA | |
| SCHEMBL12068215 | 0.76 | KDM4E (0.57) | SMN1; SMN2KDM4ELMNAMAPTHTT | |
| SCHEMBL7555207 | 0.76 | KDM4E (0.57) | SMN1; SMN2KDM4ELMNAMAPTHTT | |
| SCHEMBL7555211 | 0.76 | KDM4E (0.57) | SMN1; SMN2KDM4ELMNAMAPTHTT | |
| SCHEMBL14681397 | 0.75 | KMT2A (0.67) | CD74MIFSMN1; SMN2KDM4ELMNA | |
| SCHEMBL27846890 | 0.74 | RAB9A (0.74) | DHFRSMN1; SMN2KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112457334-A | Preparation method of phenanthroline bridged dicarballo derivative | 南京林业大学 | 2021-03-09 | — | — | CN | disclosed |