Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28591571 | 0.86 | KMT2A (0.39) | KMT2AMAPTPOLBPPARGPPARA | |
| SCHEMBL28586022 | 0.86 | KMT2A (0.39) | KMT2AHPGDDOT1LMAPTITGB1 | |
| SCHEMBL28594380 | 0.85 | KMT2A (0.40) | KMT2AHPGDMAPTRAB9AALDH1A1 | |
| SCHEMBL28596203 | 0.85 | HPGD (0.57) | KMT2AHPGDMAPTRAB9APOLB | |
| SCHEMBL28588046 | 0.85 | KMT2A (0.40) | KMT2AHPGDDOT1LPOLBPPARG | |
| SCHEMBL28594377 | 0.84 | EPHX2 (0.40) | KMT2ARAB9ASPRALDH1A1NPC1 | |
| SCHEMBL28586027 | 0.83 | GRM5 (0.43) | KMT2AHPGDMAPTRAB9APOLB | |
| SCHEMBL28585572 | 0.83 | ELANE (0.50) | KMT2AHPGDMAPTALDH1A1NPC1 | |
| SCHEMBL28590421 | 0.83 | SRD5A2 (0.48) | KMT2AHPGDMAPTRAB9AALDH1A1 | |
| SCHEMBL28588033 | 0.80 | LMNA (0.48) | KMT2AHPGDMAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121331-A | Phenoxy aromatic acid compound with cyclopropyl and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 华创合成制药股份有限公司 | 2021-07-16 | — | — | CN | claimed |