Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | FABP2 | P12104 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696193 | 0.92 | HPGD (0.43) | HPGDPPARAPTGS2MAPTSMN1; SMN2 | |
| SCHEMBL28586027 | 0.87 | GRM5 (0.43) | HPGDPOLBMAPTRAB9ALMNA | |
| SCHEMBL28585572 | 0.87 | ELANE (0.50) | HPGDELANEMAPK1SRD5A2MAPT | |
| SCHEMBL28588033 | 0.87 | LMNA (0.48) | HPGDMAPK1SRD5A2MAPTRAB9A | |
| SCHEMBL28590421 | 0.86 | SRD5A2 (0.48) | HPGDMAPK1SRD5A2MAPTRAB9A | |
| SCHEMBL28591750 | 0.85 | LMNA (0.57) | HPGDMAPK1SRD5A2LSSMAPT | |
| SCHEMBL28590432 | 0.85 | LMNA (0.42) | HPGDMAPK1MAPTRAB9ALMNA | |
| SCHEMBL28591569 | 0.85 | LMNA (0.53) | HPGDELANEPPARGPPARAFABP2 | |
| SCHEMBL28591389 | 0.85 | KMT2A (0.50) | HPGDELANEPPARGPPARAFABP2 | |
| SCHEMBL28594375 | 0.85 | KMT2A (0.43) | HPGDPPARGPPARAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121331-A | Phenoxy aromatic acid compound with cyclopropyl and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 华创合成制药股份有限公司 | 2021-07-16 | — | — | CN | claimed |