Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.60 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407111 | 0.92 | DNM1 (0.55) | DNM1RAD52NLRP1ALDH1A1LMNA | |
| SCHEMBL410748 | 0.92 | DNM1 (0.69) | DNM1RAD52NLRP1ALDH1A1MAPT | |
| SCHEMBL410011 | 0.92 | DNM1 (0.72) | DNM1RAD52NLRP1ALDH1A1LMNA | |
| SCHEMBL18925966 | 0.90 | DNM1 (0.73) | DNM1RAD52NLRP1ALDH1A1LMNA | |
| SCHEMBL408405 | 0.89 | DNM1 (0.77) | DNM1RAD52ALDH1A1LMNAMAPT | |
| SCHEMBL28581789 | 0.89 | MAPT (0.60) | DNM1RAD52NLRP1ALDH1A1LMNA | |
| SCHEMBL16604024 | 0.83 | RAD52 (0.74) | DNM1RAD52NLRP1ALDH1A1LMNA | |
| SCHEMBL21093179 | 0.82 | RAD52 (0.54) | DNM1RAD52NLRP1ALDH1A1LMNA | |
| SCHEMBL407411 | 0.81 | TSPO (0.58) | DNM1RAD52NLRP1ALDH1A1LMNA | |
| SCHEMBL17221871 | 0.80 | RAD52 (0.59) | DNM1RAD52NLRP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518750-B | Carbazole amino alcohol compound, preparation method thereof and application of carbazole amino alcohol compound in resisting parasitic diseases | 中国疾病预防控制中心寄生虫病预防控制所 | 2021-06-01 | — | — | CN | claimed |
| CN-106518750-B | Carbazole amino alcohol compound, preparation method thereof and application of carbazole amino alcohol compound in resisting parasitic diseases | 中国疾病预防控制中心寄生虫病预防控制所 | 2021-06-01 | — | — | CN | disclosed |