SCHEMBL28595012

SCHEMBL28595012

O=S(=O)(OCc1ccc(Br)cc1)C(F)(F)F

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.65
KMT2A Q03164 1/20 0.46
CA1 P00915 7/20 0.45
CA9 Q16790 5/20 0.44
IDO1 P14902 2/20 0.44
CA12 O43570 1/20 0.42
CA7 P43166 1/20 0.42
PTPRZ1 P23471 1/20 0.41
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
CA5A P35218 1/20 0.39
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
MAOB P27338 2/20 0.38
APP P05067 1/20 0.37
AR P10275 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28808949 0.98 CA2 (0.63) CA2KMT2ACA1CA9IDO1
SCHEMBL14948462 0.91 CA2 (0.55) CA2KMT2ACA1CA9IDO1
SCHEMBL16755999 0.85 CA2 (0.69) CA2KMT2ACA1CA9IDO1
SCHEMBL778365 0.83 CA2 (0.67) CA2KMT2ACA1CA9IDO1
SCHEMBL777315 0.82 CA2 (0.66) CA2KMT2ACA1CA9IDO1
SCHEMBL28351594 0.81 KMT2A (0.69) CA2KMT2ACA1CA9IDO1
Iodide SCHEMBL5828419 0.81 CA2 (0.65) CA2KMT2ACA1CA9IDO1
SCHEMBL5677195 0.81 CA2 (0.65) CA2KMT2ACA1CA9PTPRZ1
Ammonia Solution, Strong SCHEMBL28581052 0.81 CA2 (0.65) CA2KMT2ACA1CA9IDO1
SCHEMBL5676893 0.81 CA2 (0.65) CA2KMT2ACA1CA9IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112321469-A Synthetic method of dibenzyl sulfide 成都理工大学 2021-02-05 CN claimed