Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16755999 | 0.85 | CA2 (0.69) | CA2KMT2ACA1CA9PTPRZ1 | |
| SCHEMBL778365 | 0.83 | CA2 (0.67) | CA2KMT2ACA1CA9PTPRZ1 | |
| SCHEMBL777315 | 0.82 | CA2 (0.66) | CA2KMT2ACA1CA9PTPRZ1 | |
| SCHEMBL24835725 | 0.82 | CA2 (0.71) | CA2KMT2ACA1CA9PTPRZ1 | |
| SCHEMBL28351594 | 0.81 | KMT2A (0.69) | CA2KMT2ACA1CA9IDO1 | |
| SCHEMBL5677195 | 0.81 | CA2 (0.65) | CA2KMT2ACA1CA9PTPRZ1 | |
| SCHEMBL5676893 | 0.81 | CA2 (0.65) | CA2KMT2ACA1CA9PTPRZ1 | |
| SCHEMBL28595012 | 0.81 | CA2 (0.65) | CA2KMT2ACA1CA9PTPRZ1 | |
| Ammonia Solution, Strong SCHEMBL28581052 | 0.81 | CA2 (0.65) | CA2KMT2ACA1CA9PTPRZ1 | |
| Ammonia Solution, Strong SCHEMBL28512991 | 0.81 | CA2 (0.64) | CA2KMT2ACA1CA9PTPRZ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6991888-B2 | Photoresist composition for deep ultraviolet lithography comprising a mixture of photoactive compounds | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2006-01-31 | — | — | US | disclosed |
| EP-1516229-A2 | PHOTORESIST COMPOSITION FOR DEEP ULTRAVIOLET LITHOGRAPHY COMPRISING A MIXTURE OF PHOTOACTIVE COMPOUNDS | AZ Electronic Materials USA Corp. (US) | 2005-03-23 | — | — | EP | disclosed |
| US-20030235782-A1 | Photoresist composition for deep ultraviolet lithography comprising a mixture of photoactive compounds | MERCK PATENT GMBH (DE) | 2003-12-25 | — | — | US | disclosed |
| WO-2003107093-A2 | PHOTORESIST COMPOSITION FOR DEEP ULTRAVIOLET LITHOGRAPHY COMPRISING A MIXTURE OF PHOTOACTIVE COMPOUNDS | CLARIANT INTERNATIONAL LTD (CH) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030235782-A1 | Photoresist composition for deep ultraviolet lithography comprising a mixture of photoactive compounds | SUN2, UROD, ERCC1 | CA2 312/4885KMT2A 2151/4885CA1 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.