Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | WNT3A | P56704 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890937 | 0.94 | KMT2A (0.63) | KMT2ACTNNB1WNT3AALDH1A1MEN1 | |
| Benzophenone SCHEMBL4934930 | 0.79 | ALDH1A1 (0.82) | KMT2AALDH1A1MEN1L3MBTL1TDP1 | |
| SCHEMBL11064770 | 0.77 | ALDH1A1 (0.54) | KMT2ACTNNB1WNT3AALDH1A1MEN1 | |
| Benzophenone SCHEMBL27720498 | 0.77 | ALDH1A1 (0.61) | KMT2ACTNNB1WNT3AALDH1A1MEN1 | |
| SCHEMBL3226688 | 0.75 | SRD5A2 (0.56) | KMT2AALDH1A1MEN1L3MBTL1TDP1 | |
| SCHEMBL20104311 | 0.75 | SRD5A2 (0.52) | ALDH1A1MAPTTSHRNPC1RAB9A | |
| SCHEMBL28489651 | 0.75 | ALDH1A1 (0.65) | KMT2AALDH1A1MEN1L3MBTL1TDP1 | |
| Benzophenone SCHEMBL28888896 | 0.74 | ALDH1A1 (0.82) | KMT2AALDH1A1MEN1L3MBTL1TDP1 | |
| Benzophenone SCHEMBL6678679 | 0.74 | ALDH1A1 (0.82) | KMT2AALDH1A1MEN1L3MBTL1TDP1 | |
| SCHEMBL10373456 | 0.74 | P2RX7 (0.52) | KMT2ACTNNB1WNT3AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912056-B | Benzoyl pyrimidine urea compound and preparation and application thereof | 海南大学 | 2021-06-15 | — | — | CN | disclosed |
| CN-108912056-B | Benzoyl pyrimidine urea compound and preparation and application thereof | 海南大学 | 2021-06-15 | — | — | CN | disclosed |
| CN-108912056-B | Benzoyl pyrimidine urea compound and preparation and application thereof | 海南大学 | 2021-06-15 | — | — | CN | disclosed |