Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934902 | 0.86 | HTR6 (0.43) | HTR6BCHEKMT2AMMP13MMP1 | |
| SCHEMBL1935242 | 0.86 | HTR6 (0.43) | HTR6BCHEKMT2AMMP13MMP1 | |
| SCHEMBL9990721 | 0.84 | HTR6 (0.42) | HTR6BCHEMEN1KMT2AMMP13 | |
| SCHEMBL1934083 | 0.84 | HTR6 (0.42) | HTR6BCHEMEN1KMT2AMMP13 | |
| SCHEMBL9990840 | 0.81 | TACR1 (0.39) | HTR6BCHEGPR119MEN1KMT2A | |
| SCHEMBL1536189 | 0.81 | TACR1 (0.39) | HTR6BCHEGPR119MEN1KMT2A | |
| SCHEMBL18855538 | 0.81 | TACR1 (0.39) | HTR6BCHEGPR119MEN1KMT2A | |
| SCHEMBL28595287 | 0.81 | HTR6 (0.39) | HTR6BCHEGPR119MEN1KMT2A | |
| SCHEMBL28595291 | 0.81 | HTR6 (0.39) | HTR6BCHEGPR119MEN1KMT2A | |
| SCHEMBL1935169 | 0.80 | HTR6 (0.38) | HTR6BCHEGPR119MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053742-B | Novel tricyclic compounds | ABBVIE 公司 | 2021-06-15 | — | — | CN | disclosed |