SCHEMBL2859577

SCHEMBL2859577

O=C(OCCBr)C(c1ccccc1)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.63
CYP1A2 P05177 1/20 0.63
CYP2D6 P10635 1/20 0.63
CHRM1 P11229 4/20 0.62
CHRM3 P20309 4/20 0.62
CHRM2 P08172 3/20 0.62
CHRM4 P08173 3/20 0.62
ALDH1A1 P00352 6/20 0.61
CYP3A4 P08684 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
KLK7 P49862 4/20 0.51
L3MBTL1 Q9Y468 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
KMT2A Q03164 2/20 0.48
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2865466 0.87 LMNA (0.58) LMNACYP1A2CYP2D6CHRM1CHRM3
SCHEMBL2866421 0.86 CYP1A2 (0.59) LMNACYP1A2CYP2D6CHRM1CHRM3
SCHEMBL27515436 0.81 LMNA (0.47) LMNACYP1A2CYP2D6CHRM1CHRM3
SCHEMBL7333625 0.81 SRC (0.55) LMNACYP1A2CYP2D6CHRM1CHRM3
SCHEMBL2864950 0.81 CHRM1 (0.62) LMNACYP1A2CYP2D6CHRM1CHRM3
SCHEMBL2859437 0.81 CHRM1 (0.62) LMNACYP1A2CYP2D6CHRM1CHRM3
SCHEMBL9373537 0.81 CHRM1 (0.62) LMNACYP1A2CYP2D6CHRM1CHRM3
SCHEMBL7954390 0.81 CHRM1 (0.62) LMNACYP1A2CYP2D6CHRM1CHRM3
SCHEMBL19820288 0.79 CHRM1 (0.65) LMNACYP1A2CYP2D6CHRM1CHRM3
SCHEMBL3276207 0.78 CHRM3 (0.63) LMNACYP1A2CYP2D6CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1795581-B1 LUBRICATING OIL COMPOSITION CONTAINING ACRYLIC POLYMER KURARAY CO (JP) 2018-09-19 EP disclosed
US-7718588-B2 Lubricating oil additive containing acrylic polymer and lubricating oil compositions KURARAY CO., LTD. (JP) 2010-05-18 US disclosed
US-20080058234-A1 Lubricating Oil Additive Containing Acrylic Polymer and Lubricating Oil Compositions KURARAY CO., LTD. (JP) 2008-03-06 US disclosed
EP-1795581-A1 LUBRICATING OIL ADDITIVE CONTAINING ACRYLIC POLYMER AND LUBRICATING OIL COMPOSITIONS KURARAY CO., LTD. (JP) 2007-06-13 EP disclosed