SCHEMBL2864950

SCHEMBL2864950

O=C(OCCCl)C(c1ccccc1)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 4/20 0.62
CHRM3 P20309 4/20 0.62
CHRM2 P08172 3/20 0.62
CHRM4 P08173 3/20 0.62
CYP1A2 P05177 2/20 0.58
CYP2D6 P10635 2/20 0.58
LMNA P02545 2/20 0.58
ALDH1A1 P00352 7/20 0.57
CYP3A4 P08684 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
KLK7 P49862 3/20 0.51
TP53 P04637 1/20 0.49
PKM P14618 1/20 0.49
NFKB1 P19838 1/20 0.49
THPO P40225 1/20 0.49
HIF1A Q16665 1/20 0.49
L3MBTL1 Q9Y468 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
KMT2A Q03164 3/20 0.48
MEN1 O00255 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2859452 0.87 CHRM1 (0.57) CHRM1CHRM3CHRM2CHRM4CYP1A2
SCHEMBL21861228 0.86 CHRM1 (0.55) CHRM1CHRM3CHRM2CHRM4CYP1A2
SCHEMBL2866437 0.84 CHRM1 (0.56) CHRM1CHRM3CHRM2CHRM4CYP1A2
SCHEMBL9312670 0.83 LMNA (0.50) CHRM1CHRM3CHRM2CHRM4CYP1A2
SCHEMBL10445350 0.81 CHRM1 (0.46) CHRM1CHRM3CHRM2CHRM4CYP1A2
SCHEMBL2859577 0.81 LMNA (0.63) CHRM1CHRM3CHRM2CHRM4CYP1A2
SCHEMBL9373537 0.81 CHRM1 (0.62) CHRM1CHRM3CHRM2CHRM4CYP1A2
SCHEMBL7954390 0.81 CHRM1 (0.62) CHRM1CHRM3CHRM2CHRM4CYP1A2
SCHEMBL2859437 0.81 CHRM1 (0.62) CHRM1CHRM3CHRM2CHRM4CYP1A2
SCHEMBL19820288 0.79 CHRM1 (0.65) CHRM1CHRM3CHRM2CHRM4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1795581-B1 LUBRICATING OIL COMPOSITION CONTAINING ACRYLIC POLYMER KURARAY CO (JP) 2018-09-19 EP disclosed
US-7718588-B2 Lubricating oil additive containing acrylic polymer and lubricating oil compositions KURARAY CO., LTD. (JP) 2010-05-18 US disclosed
US-20080058234-A1 Lubricating Oil Additive Containing Acrylic Polymer and Lubricating Oil Compositions KURARAY CO., LTD. (JP) 2008-03-06 US disclosed
EP-1795581-A1 LUBRICATING OIL ADDITIVE CONTAINING ACRYLIC POLYMER AND LUBRICATING OIL COMPOSITIONS KURARAY CO., LTD. (JP) 2007-06-13 EP disclosed