Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 15/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096257 | 0.86 | POLB (0.67) | POLBNR1H4ALDH1A1GAAMAPT | |
| SCHEMBL22790236 | 0.82 | POLB (0.58) | POLBNR1H4ALDH1A1GAAMAPT | |
| SCHEMBL22397165 | 0.81 | POLB (0.50) | POLBNR1H4ALDH1A1GAA | |
| SCHEMBL22790342 | 0.81 | POLB (0.57) | POLBNR1H4ALDH1A1GAAMAPT | |
| SCHEMBL22772582 | 0.79 | NR1H4 (0.50) | POLBNR1H4ALDH1A1GAA | |
| SCHEMBL1999474 | 0.79 | POLB (0.51) | POLBNR1H4ALDH1A1GAAMAPT | |
| SCHEMBL4338523 | 0.77 | POLB (0.49) | POLBNR1H4ALDH1A1GAAMAPT | |
| SCHEMBL22570976 | 0.76 | NR1H4 (0.49) | POLBNR1H4ALDH1A1GAA | |
| SCHEMBL22772592 | 0.76 | PPARG (0.54) | POLBNR1H4ALDH1A1GAAMAPT | |
| SCHEMBL2002892 | 0.74 | NR1H4 (0.54) | POLBNR1H4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430998-B | Azabicyclo derivatives, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-07-09 | — | — | CN | disclosed |