SCHEMBL28596095

SCHEMBL28596095

C[S+]([O-])c1cc(Cl)ccc1Br

nearest known ligand 0.31

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.31
TSHR P16473 4/20 0.31
HTT P42858 2/20 0.31
MAPK1 P28482 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
CCR2 P41597 1/20 0.31
TP53 P04637 1/20 0.31
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30
CYP3A4 P08684 1/20 0.30
PYCR1 P32322 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28602950 0.83 TSHR (0.34) TSHRHTTLMNAHPGDCCR2
SCHEMBL13040417 0.78 TP53 (0.44) TSHRHTTMAPK1LMNATP53
SCHEMBL27431129 0.77 CYP3A4 (0.45) LMNATP53CYP3A4
SCHEMBL18613087 0.75
SCHEMBL4570571 0.74
SCHEMBL17733556 0.74 TP53 (0.44) TSHRHTTMAPK1LMNATP53
SCHEMBL21879772 0.73 S100A4 (0.36) S100A4
SCHEMBL31223185 0.73 S100A4 (0.36) S100A4
SCHEMBL8297182 0.72
SCHEMBL23702742 0.72 ENPP2 (0.35) TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113121584-B Heterocyclic compound and organic electroluminescent device comprising same 武汉尚赛光电科技有限公司 2024-05-14 CN disclosed
CN-113121584-A Heterocyclic compound and organic electroluminescent device comprising same 武汉尚赛光电科技有限公司 2021-07-16 CN disclosed