SCHEMBL28596106

SCHEMBL28596106

Cc1ccccc1-c1ccc2[nH]nnc2c1-c1ccccc1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.40
TRPA1 O75762 1/20 0.38
RAB9A P51151 6/20 0.37
SMN1; SMN2 Q16637 6/20 0.37
NPC1 O15118 5/20 0.37
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
HPGD P15428 5/20 0.35
ALDH1A1 P00352 4/20 0.35
NPSR1 Q6W5P4 3/20 0.35
HTT P42858 1/20 0.35
DCUN1D1 Q96GG9 2/20 0.34
PKM P14618 1/20 0.34
KDM4E B2RXH2 1/20 0.34
PRNP P04156 1/20 0.34
PPARG P37231 1/20 0.34
MAPK10 P53779 1/20 0.34
NCOA2 Q15596 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28680551 0.87 TRPA1 (0.39) GAATRPA1RAB9ASMN1; SMN2NPC1
SCHEMBL7645989 0.84 GAA (0.38) GAATRPA1RAB9ASMN1; SMN2NPC1
SCHEMBL31625576 0.84 HPGD (0.39) GAATRPA1RAB9ASMN1; SMN2NPC1
SCHEMBL504322 0.84 HPGD (0.39) GAATRPA1RAB9ASMN1; SMN2NPC1
SCHEMBL2249705 0.81 GAA (0.43) GAATRPA1RAB9ASMN1; SMN2NPC1
SCHEMBL28674437 0.80 GAA (0.35) GAATRPA1RAB9ASMN1; SMN2NPC1
SCHEMBL28410794 0.78 TRPA1 (0.43) TRPA1ALDH1A1TSHR
SCHEMBL28650673 0.77 MEN1 (0.30) NPSR1MEN1LMNAKMT2AMAPT
SCHEMBL15020493 0.75 MGAM (0.41) GAARAB9ASMN1; SMN2NPC1HPGD
SCHEMBL1462356 0.73 AKT2 (0.44) RAB9ASMN1; SMN2NPC1CASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110944957-B Heat-resistant radiation-curable coating for optical fibers 科思创(荷兰)有限公司 2022-07-08 CN disclosed
CN-114144386-A Radiation curable compositions for coating optical fibers with enhanced high speed processability 科思创(荷兰)有限公司 2022-03-04 CN disclosed
CN-113165971-A Filled radiation curable compositions for coating optical fibers and coatings produced therefrom MS控股有限公司 2021-07-23 CN disclosed