SCHEMBL28596107

SCHEMBL28596107

[N-]=[N+]=NCc1cccc(-c2ncc[nH]2)n1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
NISCH Q9Y2I1 2/20 0.36
MTOR P42345 1/20 0.36
ADK P55263 1/20 0.36
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
IDO1 P14902 1/20 0.32
ADRA2A P08913 1/20 0.32
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30
HTR1A P08908 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16560321 0.77 KDM4E (0.52) ALDH1A1KDM4EADORA2A
SCHEMBL7419102 0.76 NISCH (0.42) ALDH1A1KDM4ENISCHMTORADK
SCHEMBL197279 0.75 NISCH (0.54) ALDH1A1KDM4ENISCHMTORADK
SCHEMBL15259719 0.75 HRH4 (0.47) ALDH1A1KDM4E
SCHEMBL13830975 0.71 NISCH (0.39) ALDH1A1NISCHMTORADKMEN1
SCHEMBL29079328 0.69 NISCH (0.47) ALDH1A1KDM4ENISCHMTORADK
SCHEMBL20417166 0.69 HRH4 (0.41) ALDH1A1KDM4E
SCHEMBL24915610 0.67 KDM4E (0.40) ALDH1A1KDM4E
SCHEMBL17258436 0.67 HRH4 (0.44) ALDH1A1KDM4E
SCHEMBL14304159 0.67 NISCH (0.46) ALDH1A1KDM4ENISCHMTORADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113121502-A Heteroaromatic hydrocarbon compound, intermediate, composition and application 山东铂源生物医药有限公司 2021-07-16 CN disclosed