SCHEMBL197279

SCHEMBL197279

c1cc(-c2ncc[nH]2)nc(-c2ncc[nH]2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 2/20 0.54
MTOR P42345 1/20 0.54
ADK P55263 1/20 0.54
ALDH1A1 P00352 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ADRA2A P08913 5/20 0.44
KDM4E B2RXH2 3/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
ALPL P05186 1/20 0.43
HSP90AA1 P07900 1/20 0.43
ALPI P09923 1/20 0.43
ALPG P10696 1/20 0.43
ALOX15 P16050 1/20 0.43
MAPK1 P28482 1/20 0.43
CCR1 P32246 1/20 0.43
HTT P42858 1/20 0.43
CCR5 P51681 1/20 0.43
CCR8 P51685 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20987228 0.89 NISCH (0.63) NISCHMTORADKALDH1A1MEN1
SCHEMBL24575910 0.89 KDM4E (0.64) NISCHMTORADKALDH1A1ADRA2A
SCHEMBL29079328 0.88 NISCH (0.47) NISCHMTORADKALDH1A1MEN1
SCHEMBL31374443 0.86 NISCH (0.46) NISCHMTORADKALDH1A1MEN1
SCHEMBL309114 0.86 CCR1 (0.54) NISCHMTORADKALDH1A1MEN1
SCHEMBL14304159 0.86 NISCH (0.46) NISCHMTORADKALDH1A1MEN1
SCHEMBL3050014 0.86 NISCH (0.46) NISCHMTORADKALDH1A1MEN1
SCHEMBL4766313 0.86 NISCH (0.46) NISCHMTORADKALDH1A1MEN1
SCHEMBL12354743 0.84 NISCH (0.41) NISCHMTORADKALDH1A1MEN1
SCHEMBL7419102 0.82 NISCH (0.42) NISCHMTORADKALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115466275-B Latent fingerprint fluorescent visual identification probe and method on substrate 复旦大学 2025-05-09 CN claimed
CN-119823102-A Pyridine imidazole derivative and preparation method and application thereof 广东科学技术职业学院 2025-04-15 CN claimed
CN-118359586-A Spin cross conduction bifunctional complex, preparation method and application thereof 大连理工大学 2024-07-19 CN claimed
CN-115466275-A Fluorescent visual identification probe and method for latent fingerprints on substrate 复旦大学 2022-12-13 CN claimed
CN-113336778-A Fluorescent visual identification probe and method for latent fingerprints on substrate 复旦大学 2021-09-03 CN claimed
WO-2018213821-A1 CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME THE GEORGE WASHINGTON UNIVERSITY (US) 2018-11-22 WO claimed
EP-2920186-B1 NOVEL GOLD(III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT AND THIOL DETECTION UNIV HONG KONG (CN) 2018-06-27 EP claimed
EP-2920186-A1 NOVEL GOLD(III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT AND THIOL DETECTION The University of Hong Kong (CN) 2015-09-23 EP claimed
US-8828984-B2 Gold(III) complexes containing N-heterocyclic carbene ligand, synthesis, and their applications in cancer treatment and thiol detection THE UNIVERSITY OF HONG KONG (CN) 2014-09-09 US claimed
US-20140142080-A1 NOVEL GOLD(III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT AND THIOL DETECTION UNIVERSITY OF HONG KONG (CN) 2014-05-22 US claimed
WO-2014075394-A1 NOVEL GOLD(III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT AND THIOL DETECTION THE UNIVERSITY OF HONG KONG (CN) 2014-05-22 WO claimed
CN-122011354-A Biimidazole catalyst for liquid crystal polyarylester synthesis and application thereof 浙江海利得科技有限公司 2026-05-12 CN disclosed
US-20250377357-A1 SELF-ACTUATING SIGNAL PRODUCING DETECTION DEVICES AND METHODS RED IVORY LLC (US) 2025-12-11 US disclosed
CN-115466275-B Latent fingerprint fluorescent visual identification probe and method on substrate 复旦大学 2025-05-09 CN disclosed
CN-115466275-B Latent fingerprint fluorescent visual identification probe and method on substrate 复旦大学 2025-05-09 CN disclosed
US-6338790-B1 DETECTION OF BIOANALYTES IN A SMALL VOLUME SAMPLE; CONCENTRATION OF A BIOMOLECULE, SUCH AS GLUCOSE OR LACTATE, USING TECHNIQUES SUCH AS COULOMETRY, AMPEROMETRY, AND POTENTIOMETRY. AN ENZYME CAPABLE OF CATALYZING THE THERASENSE, INC. 2002-01-15 US disclosed
US-6299757-B1 ANALYTICAL SENSORS FOR THE DETECTION OF BIOANALYTES; ESPECIALLY MONITORING GLUCOSE LEVELS IN DIABETIC PATIENTS THERASENSE, INC. 2001-10-09 US disclosed
US-6294281-B1 Biological fuel cell and method THERASENSE, INC. 2001-09-25 US disclosed
EP-1119637-A1 SMALL VOLUME $i(IN VITRO) ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR Therasense, Inc. (US) 2001-08-01 EP disclosed
WO-2000020626-A1 SMALL VOLUME IN VITRO ANALYTE SENSOR WITH DIFFUSIBLE OR NON-LEACHABLE REDOX MEDIATOR THERASENSE, INC. (US) 2000-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140142080-A1 NOVEL GOLD(III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR APPLICATIONS IN CANCER TREATMENT AND THIOL DETECTION TXNRD3, TXNRD1, TXN NISCH 721/4885MTOR 3855/4885ADK 3130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.