SCHEMBL28596158

SCHEMBL28596158

CC1CCCO1.[Li]CCCC

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.31
NPC1 O15118 1/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
CYP1A2 P05177 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL1664733 0.87 EPHX1 (0.45) EPHX1SMN1; SMN2NPC1TP53HPGD
Heptane SCHEMBL241041 0.85 EPHX1 (0.48) EPHX1SMN1; SMN2NPC1TP53HPGD
Propane SCHEMBL29260697 0.80
Butyl Alcohol SCHEMBL28856285 0.80 ALDH1A1 (0.44) EPHX1SMN1; SMN2NPC1TP53HPGD
Bromide SCHEMBL28886830 0.78 EPHX1 (0.34) EPHX1SMN1; SMN2NPC1TP53HPGD
1-Pentanol SCHEMBL28201262 0.78 SMN1; SMN2 (0.46) EPHX1SMN1; SMN2NPC1TP53HPGD
SCHEMBL16005388 0.78
SCHEMBL10067 0.78
SCHEMBL31673148 0.78
SCHEMBL2473867 0.78 NOS2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113121518-B Preparation method of tedizolid impurity 北京福元医药股份有限公司 2022-06-28 CN disclosed
CN-113121518-A Preparation method of tedizolid impurity 北京福元医药股份有限公司 2021-07-16 CN disclosed