SCHEMBL28596170

SCHEMBL28596170

O=C(Nc1cccc2cccnc12)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 4/20 0.84
HDAC6 Q9UBN7 1/20 0.75
L3MBTL1 Q9Y468 2/20 0.73
TDP1 Q9NUW8 1/20 0.73
GAA P10253 1/20 0.73
MAPT P10636 7/20 0.68
TP53 P04637 2/20 0.68
KMT2A Q03164 4/20 0.65
POLB P06746 1/20 0.65
HTT P42858 1/20 0.65
NPC1 O15118 3/20 0.64
RAB9A P51151 3/20 0.64
MEN1 O00255 3/20 0.64
CASP3 P42574 1/20 0.64
SENP8 Q96LD8 1/20 0.64
SENP7 Q9BQF6 1/20 0.64
SENP6 Q9GZR1 1/20 0.64
ALDH1A1 P00352 1/20 0.64
NPSR1 Q6W5P4 1/20 0.64
KDM4E B2RXH2 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29434873 0.91 KDR (1.00) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL6260903 0.91 KDR (1.00) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL3210721 0.86 MAPT (0.64) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL15270551 0.86 HDAC6 (0.79) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL29647754 0.86 HDAC6 (1.00) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL19631488 0.86 HDAC6 (1.00) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL15441206 0.85 KDR (0.77) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL16456332 0.84 HDAC6 (0.77) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL17552183 0.84 HDAC6 (0.77) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL15093487 0.84 HDAC6 (0.77) KDRHDAC6L3MBTL1TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117945998-A Ortho-selective deuteration method for aromatic amide compounds 浙大宁波理工学院 2024-04-30 CN disclosed
CN-117486795-A Preparation method of deuterated amide aromatic compound 浙大宁波理工学院 2024-02-02 CN disclosed
CN-111519204-B Method for preparing N- (5-chloro-8-quinolyl) benzamide compound by adopting electrochemical microchannel reaction device 南京工业大学 2021-06-29 CN disclosed
CN-111519204-A Method for preparing N- (5-chloro-8-quinolyl) benzamide compound by adopting electrochemical microchannel reaction device 南京工业大学 2020-08-11 CN disclosed