SCHEMBL29434873

SCHEMBL29434873

O=C(Nc1cccc2cccnc12)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 7/20 1.00
HDAC6 Q9UBN7 1/20 0.78
L3MBTL1 Q9Y468 2/20 0.76
TDP1 Q9NUW8 1/20 0.76
GAA P10253 1/20 0.76
HTT P42858 1/20 0.76
KMT2A Q03164 4/20 0.75
RAB9A P51151 4/20 0.75
MEN1 O00255 3/20 0.75
NPC1 O15118 3/20 0.75
ALDH1A1 P00352 1/20 0.75
NPSR1 Q6W5P4 1/20 0.75
MAPT P10636 4/20 0.71
TP53 P04637 1/20 0.71
SMN1; SMN2 Q16637 2/20 0.68
KDM4E B2RXH2 2/20 0.68
POLB P06746 1/20 0.67
CASP3 P42574 1/20 0.67
SENP8 Q96LD8 1/20 0.67
SENP7 Q9BQF6 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6260903 1.00 KDR (1.00) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL28596170 0.91 KDR (0.84) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL19631488 0.88 HDAC6 (1.00) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL15270551 0.88 HDAC6 (0.79) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL29647754 0.88 HDAC6 (1.00) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL15441206 0.87 KDR (0.77) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL15328429 0.87 TDP1 (1.00) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL17552183 0.87 HDAC6 (0.77) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL16456332 0.87 HDAC6 (0.77) KDRHDAC6L3MBTL1TDP1GAA
SCHEMBL6645868 0.87 HTT (1.00) KDRHDAC6L3MBTL1TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 EP claimed
EP-4514949-A1 METHODS AND COMPOSITIONS FOR TREATING VISION LOSS Hadasit Medical Research Services&Development Ltd. (IL) 2025-03-05 EP claimed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 WO claimed
CN-114478492-B From CF 3 SO 2 Na-mediated method for cross dehydrogenation and coupling of photocatalytic heteroarene and aliphatic compound bond 南京工业大学 2024-04-09 CN claimed
WO-2023211857-A1 METHODS AND COMPOSITIONS FOR TREATING VISION LOSS Lineage Cell Therapeutics, Inc. (US) 2023-11-02 WO claimed
CN-114478492-A By CF3SO2Na-mediated photocatalytic method for cross dehydrogenation coupling of heteroarene and aliphatic compound bonds 南京工业大学 2022-05-13 CN claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 EP disclosed
CN-119998260-A Process for preparing amides from esters 巴斯夫欧洲公司 2025-05-13 CN disclosed
WO-2025059689-A1 COMPOSITIONS AND METHODS FOR PROMOTING THE GENERATION OF PHARYNGEAL FOREGUT ENDODERM AND ITS DERIVATIVES UNIVERSITY OF MASSACHUSETTS (US) 2025-03-20 WO disclosed
EP-4514949-A1 METHODS AND COMPOSITIONS FOR TREATING VISION LOSS Hadasit Medical Research Services&Development Ltd. (IL) 2025-03-05 EP disclosed
CN-113811605-B Method for obtaining eye progenitor cells from human pluripotent stem cells 诺和诺德股份有限公司 2024-09-27 CN disclosed
CN-113461670-B Novel compounds as inhibitors of rearrangement kinase during transfection 南京天印健华医药科技有限公司 2024-08-09 CN disclosed
CN-111777593-B Novel compounds as inhibitors of rearrangement kinase during transfection 南京天印健华医药科技有限公司 2024-07-23 CN disclosed
CN-113336784-B 3-substituted benzofluorenone or 3-substituted naphthofluorenone derivatives and synthesis method thereof 上海大学 2022-11-18 CN disclosed
CN-109843874-B Phthalazine derivatives useful as inhibitors of PARP1, PARP2 and/or tubulin for the treatment of cancer 加利福尼亚大学董事会 2022-05-27 CN disclosed
CN-114478492-A By CF3SO2Na-mediated photocatalytic method for cross dehydrogenation coupling of heteroarene and aliphatic compound bonds 南京工业大学 2022-05-13 CN disclosed
CN-114276270-A Synthesis method of compound with amido bond 湖北文理学院 2022-04-05 CN disclosed
CN-111592489-B Method for selective C5 halogenation of quinoline skeleton of quinoline amide 浙江工业大学 2022-03-18 CN disclosed
WO-2022054924-A1 MEDIUM FOR TISSUE FOR TRANSPLANTATION 大日本住友製薬株式会社 2022-03-17 WO disclosed
WO-2022054925-A1 COMPLEX CONTAINING NEURAL RETINA-CONTAINING CELL AGGREGATES AND MATRIX, AND METHOD FOR MANUFACTURING SAME 国立研究開発法人理化学研究所 2022-03-17 WO disclosed