Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28605208 | 0.85 | ELANE (0.73) | ELANEPOLBKMT2AALDH1A1HPGD | |
| SCHEMBL28585646 | 0.84 | ELANE (0.68) | ELANEPOLBKMT2AALDH1A1HPGD | |
| SCHEMBL10483701 | 0.84 | ELANE (1.00) | ELANEPOLBKMT2AALDH1A1MEN1 | |
| SCHEMBL28590426 | 0.83 | ELANE (0.71) | ELANEPOLBKMT2AALDH1A1MEN1 | |
| SCHEMBL28591383 | 0.83 | ELANE (0.71) | ELANEPOLBKMT2AALDH1A1MEN1 | |
| SCHEMBL28581291 | 0.83 | ELANE (0.66) | ELANEPOLBKMT2AHPGDMEN1 | |
| SCHEMBL6689211 | 0.81 | POLB (0.58) | ELANEPOLBKMT2AMEN1HTT | |
| SCHEMBL28588041 | 0.77 | ELANE (0.66) | ELANEPOLBKMT2AALDH1A1HPGD | |
| SCHEMBL10455653 | 0.77 | ELANE (0.45) | ELANEPOLBKMT2AALDH1A1HPGD | |
| SCHEMBL27559710 | 0.77 | KMT2A (0.68) | ELANEPOLBKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121331-A | Phenoxy aromatic acid compound with cyclopropyl and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 华创合成制药股份有限公司 | 2021-07-16 | — | — | CN | claimed |