Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | IAPP | P10997 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27456559 | 0.89 | NPC1 (0.47) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL2916047 | 0.89 | IGF1R (0.43) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL673963 | 0.86 | HTT (0.52) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL29612324 | 0.86 | HTT (0.52) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL28790589 | 0.86 | NPC1 (0.45) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL3808961 | 0.85 | BACE1 (0.53) | MAPK1HTTCNR1CNR2IGF1R | |
| Methane SCHEMBL27924017 | 0.85 | HTT (0.50) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL9489396 | 0.82 | ESR1 (0.48) | MAPK1HTTRAB9ACNR1CNR2 | |
| SCHEMBL8465182 | 0.82 | IGF1R (0.41) | NPSR1KAT8CNR1CNR2IGF1R | |
| SCHEMBL28646119 | 0.81 | NPC1 (0.50) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164941-A | Catalyst system comprising a metathesis catalyst and at least one phenolic compound and process for the metathesis of nitrile rubber (NBR) using the catalyst system | 阿朗新科德国有限责任公司 | 2021-07-23 | — | — | CN | disclosed |