Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 7/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461823 | 0.89 | IGF1R (0.41) | IGF1RALOX15KAT8GRIN2DGRIN2A | |
| SCHEMBL11806538 | 0.87 | IGF1R (0.44) | IGF1RALOX15KAT8GRIN2DGRIN2A | |
| SCHEMBL8462078 | 0.87 | ALOX15 (0.44) | IGF1RALOX15KAT8GRIN2DGRIN2A | |
| SCHEMBL8461463 | 0.87 | ALOX15 (0.44) | IGF1RALOX15KAT8GRIN2DGRIN2A | |
| SCHEMBL8461820 | 0.87 | KAT8 (0.45) | KAT8HTR1ACYP3A4PPARAESR1 | |
| SCHEMBL27488314 | 0.83 | APP (0.46) | GRIN2DGRIN2AGRIN2BGRIN2CHTR1A | |
| SCHEMBL28596261 | 0.82 | NPC1 (0.49) | IGF1RALOX15KAT8CYP3A4NPSR1 | |
| SCHEMBL28571585 | 0.81 | ALOX15 (0.46) | IGF1RALOX15GRIN2DGRIN2AGRIN2B | |
| SCHEMBL2916047 | 0.81 | IGF1R (0.43) | IGF1RALOX15KAT8NPSR1PPARA | |
| SCHEMBL27489333 | 0.80 | YWHAG (0.42) | CYP3A4MEN1CYP1A2POLBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548906-B1 | Method for preparing nuclear-substituted salicylic acid metal salts and color developer for pressure-sensitive recording sheets | SANKO KAIHATSU KAGAKU KENK (JP) | 1999-03-31 | — | — | EP | disclosed |
| US-5393332-A | Salt of salicylic acid | SANKO KAIHATSU KAGAKU KENKYUSHO (JP) | 1995-02-28 | — | — | US | disclosed |
| EP-0548906-A2 | Method for preparing nuclear-substituted salicylic acids and metal salts thereof | Sanko Kaihatsu Kagaku Kenkyusho (JP) | 1993-06-30 | — | — | EP | disclosed |