Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL5425195 | 0.92 | ALDH1A1 (0.54) | TSHRGPR84FFAR1EPHX1SMN1; SMN2 | |
| Bicarbonate SCHEMBL30041221 | 0.86 | TSHR (0.59) | TSHRGPR84EPHX1ALDH1A1S1PR2 | |
| Bicarbonate SCHEMBL28432751 | 0.86 | TSHR (0.59) | TSHRGPR84EPHX1ALDH1A1S1PR2 | |
| Lactic Acid SCHEMBL28770151 | 0.85 | ALDH1A1 (0.46) | TSHRGPR84FFAR1ALDH1A1S1PR2 | |
| Myralact SCHEMBL2734628 | 0.85 | ALDH1A1 (0.46) | TSHRGPR84FFAR1EPHX1SMN1; SMN2 | |
| Lactic Acid SCHEMBL25181229 | 0.84 | TP53 (0.50) | TSHRGPR84FFAR1EPHX1SMN1; SMN2 | |
| Acetic Acid SCHEMBL5860277 | 0.84 | TSHR (0.56) | TSHREPHX1ALDH1A1S1PR2S1PR4 | |
| Acetic Acid SCHEMBL7566092 | 0.84 | TSHR (0.56) | TSHREPHX1ALDH1A1S1PR2S1PR4 | |
| Acetic Acid SCHEMBL31296675 | 0.84 | TSHR (0.56) | TSHREPHX1ALDH1A1S1PR2S1PR4 | |
| Dodecane SCHEMBL6896604 | 0.83 | GPR84 (0.62) | TSHRGPR84FFAR1ALDH1A1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166289-B | Composite resin aqueous dispersion and method for producing composite resin aqueous dispersion | 三洋化成工业株式会社 | 2023-04-07 | — | — | CN | disclosed |
| CN-113166289-A | Composite resin aqueous dispersion and method for producing composite resin aqueous dispersion | 三洋化成工业株式会社 | 2021-07-23 | — | — | CN | disclosed |