Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 15/20 | 0.85 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854119 | 0.92 | HPGD (0.73) | CCR1HPGDNPSR1KDM4EHSP90AA1 | |
| SCHEMBL5678637 | 0.91 | CCR1 (1.00) | CCR1HPGDNPSR1KDM4EHSP90AA1 | |
| SCHEMBL2859642 | 0.88 | CCR1 (0.73) | CCR1HPGDKDM4EMAPTPOLB | |
| SCHEMBL2858213 | 0.86 | CCR1 (0.69) | CCR1HPGDMAPTPOLBMAPK14 | |
| SCHEMBL2856089 | 0.85 | HPGD (1.00) | CCR1HPGDNPC1POLBRAB9A | |
| SCHEMBL1256358 | 0.84 | CCR1 (1.00) | CCR1 | |
| SCHEMBL2854225 | 0.83 | CCR1 (0.60) | CCR1HPGDNPSR1KDM4EHSP90AA1 | |
| SCHEMBL2860195 | 0.82 | CCR1 (0.70) | CCR1HPGDNPSR1KDM4E | |
| SCHEMBL2860538 | 0.81 | KDM4E (0.61) | CCR1HPGDKDM4EMAPTPOLB | |
| SCHEMBL25781908 | 0.81 | CCR1 (0.66) | CCR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |