Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 18/20 | 0.54 |
| ▸ | PHGDH | O43175 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28596432 | 1.00 | RORC (0.54) | RORCPHGDH | |
| SCHEMBL28592305 | 0.84 | RORC (0.56) | RORC | |
| SCHEMBL28592306 | 0.84 | RORC (0.56) | RORC | |
| SCHEMBL21936291 | 0.81 | RORC (0.41) | RORCPHGDH | |
| SCHEMBL30485945 | 0.79 | RORC (0.53) | RORCPHGDH | |
| SCHEMBL30065136 | 0.79 | RORC (0.53) | RORCPHGDH | |
| SCHEMBL23636782 | 0.79 | RORC (0.51) | RORC | |
| SCHEMBL30065092 | 0.78 | KAT6A (0.50) | RORCPHGDH | |
| SCHEMBL28708836 | 0.77 | RORC (0.55) | RORC | |
| SCHEMBL28708837 | 0.77 | RORC (0.55) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800904-A | ROR gamma inhibitors containing sulfonyl structures | 正大天晴药业集团股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-113166061-B | ROR gamma inhibitors containing sulfonyl structures | 正大天晴药业集团股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-113166061-A | ROR gamma inhibitors containing sulfonyl structures | 正大天晴药业集团股份有限公司 | 2021-07-23 | — | — | CN | disclosed |