Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23642254 | 0.89 | MAPT (0.47) | RORCMAPTALDH1A1HPGDTSHR | |
| SCHEMBL23636724 | 0.84 | RORC (0.55) | RORC | |
| SCHEMBL23636838 | 0.83 | RORC (0.54) | RORC | |
| SCHEMBL23636622 | 0.79 | ACACB (0.51) | RORC | |
| SCHEMBL28596428 | 0.79 | RORC (0.54) | RORC | |
| SCHEMBL28596432 | 0.79 | RORC (0.54) | RORC | |
| SCHEMBL28671062 | 0.79 | RORC (0.49) | RORC | |
| SCHEMBL30065136 | 0.77 | RORC (0.53) | RORCALDH1A1KMT2A | |
| SCHEMBL30485945 | 0.77 | RORC (0.53) | RORCALDH1A1KMT2A | |
| SCHEMBL23636762 | 0.76 | WDR91 (0.55) | RORCMAPTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021139599-A1 | RORγT INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 东莞市东阳光新药研发有限公司 | 2021-07-15 | — | — | WO | disclosed |