Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306433 | 1.00 | LMNA (0.53) | LMNAALDH1A1THRBTDP1MAPT | |
| SCHEMBL4526347 | 0.86 | — | — | |
| SCHEMBL12764851 | 0.82 | — | — | |
| SCHEMBL17260452 | 0.82 | — | — | |
| SCHEMBL18422671 | 0.82 | — | — | |
| SCHEMBL17260442 | 0.82 | — | — | |
| SCHEMBL16675568 | 0.82 | — | — | |
| SCHEMBL16820909 | 0.82 | — | — | |
| SCHEMBL4523537 | 0.82 | GRIK1 (0.39) | LMNAALDH1A1THRBUSP2CYP3A4 | |
| SCHEMBL7453785 | 0.80 | ALDH1A1 (0.35) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195473-A | Tricyclic compound as STING agonist and preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-30 | — | — | CN | disclosed |