Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 14/20 | 0.67 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.67 |
| ▸ | PTGES | O14684 | 2/20 | 0.50 |
| ▸ | PNLIP | P16233 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | BCL9 | O00512 | 3/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demethylcryptojaponol SCHEMBL13532270 | 1.00 | FDPS (0.67) | FDPSGGPS1PTGESPNLIPMEN1 | |
| Demethylcryptojaponol SCHEMBL16006713 | 1.00 | FDPS (0.67) | FDPSGGPS1PTGESPNLIPMEN1 | |
| Cryptojaponol SCHEMBL18290238 | 0.89 | FDPS (0.60) | FDPSGGPS1PTGESPNLIPMEN1 | |
| Cryptojaponol SCHEMBL30600453 | 0.89 | FDPS (0.60) | FDPSGGPS1PTGESPNLIPMEN1 | |
| Cryptojaponol SCHEMBL13532267 | 0.89 | FDPS (0.60) | FDPSGGPS1PTGESPNLIPMEN1 | |
| SCHEMBL13533287 | 0.85 | FDPS (0.54) | FDPSGGPS1PTGESPNLIPMEN1 | |
| Sugiol SCHEMBL28605319 | 0.81 | SOD1 (0.58) | FDPSGGPS1PTGESPNLIPMEN1 | |
| Sugiol SCHEMBL1086916 | 0.81 | SOD1 (0.58) | FDPSGGPS1PTGESPNLIPMEN1 | |
| Sugiol SCHEMBL17407685 | 0.81 | SOD1 (0.58) | FDPSGGPS1PTGESPNLIPMEN1 | |
| 6-Alpha-Hydroxydemethyl-Cryptojaponol SCHEMBL18290237 | 0.81 | SOD1 (0.54) | FDPSGGPS1PTGESPNLIPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113122512-B | Salvia miltiorrhiza P450 mutant for preparing tanshinone compounds | 中国中医科学院中药研究所 | 2022-05-17 | — | — | CN | disclosed |
| CN-113122513-B | Salvia miltiorrhiza P450 mutant and application thereof | 中国中医科学院中药研究所 | 2022-05-17 | — | — | CN | disclosed |
| CN-113122512-A | Salvia miltiorrhiza P450 mutant for preparing tanshinone compounds | 中国中医科学院中药研究所 | 2021-07-16 | — | — | CN | disclosed |
| CN-113122513-A | Salvia miltiorrhiza P450 mutant and application thereof | 中国中医科学院中药研究所 | 2021-07-16 | — | — | CN | disclosed |