Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848514 | 0.85 | NOTUM (0.46) | TDP1NOTUMPTGER4ALDH1A1RAB9A | |
| SCHEMBL28595171 | 0.82 | ALDH1A1 (0.51) | NOTUMALDH1A1RAB9AMAPTKDM4E | |
| SCHEMBL10177554 | 0.77 | TP53 (0.44) | TDP1NOTUMPTGER4ALDH1A1RAB9A | |
| SCHEMBL10177755 | 0.77 | TAAR1 (0.48) | TDP1NOTUMPTGER4ALDH1A1RAB9A | |
| SCHEMBL14848509 | 0.76 | HTT (0.53) | TDP1PTGER4ALDH1A1FFAR1MAPT | |
| SCHEMBL8977412 | 0.73 | IDH1 (0.54) | TDP1CYP4F2CYP4A11HSD17B10HIF1A | |
| SCHEMBL28637299 | 0.73 | HPGD (0.46) | TDP1ALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL28854523 | 0.73 | MAPK14 (0.38) | FAAHALDH1A1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL22251662 | 0.69 | TDP1 (0.71) | TDP1RAB9ASMN1; SMN2FFAR1GAA | |
| SCHEMBL1938644 | 0.69 | TDP1 (0.71) | TDP1RAB9ASMN1; SMN2FFAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110305143-B | Furan [2,3-c ] pyridine derivative and preparation method and application thereof | 济南新科医药科技有限公司 | 2021-03-09 | — | — | CN | disclosed |