Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358651 | 0.85 | IDH1 (0.57) | IDH1TDP1DAOCALM1BCL2 | |
| SCHEMBL27719076 | 0.83 | IDH1 (0.58) | IDH1TDP1DAOCALM1BCL2 | |
| SCHEMBL21153740 | 0.82 | IDH1 (0.50) | IDH1TDP1DAOCALM1BCL2 | |
| SCHEMBL11483794 | 0.78 | IDH1 (0.57) | IDH1DAOCALM1BCL2BCL2L1 | |
| SCHEMBL15978541 | 0.78 | IDH1 (0.53) | IDH1DAOCALM1BCL2BCL2L1 | |
| SCHEMBL11195540 | 0.78 | IDH1 (0.53) | IDH1TDP1DAOCALM1BCL2 | |
| SCHEMBL11173312 | 0.78 | IDH1 (0.53) | IDH1TDP1DAOCALM1BCL2 | |
| SCHEMBL11040268 | 0.76 | IDH1 (0.64) | IDH1DAOCALM1BCL2BCL2L1 | |
| SCHEMBL28226448 | 0.75 | TSHR (0.54) | IDH1DAOCALM1TSHR | |
| SCHEMBL15977315 | 0.74 | IDH1 (0.49) | IDH1TDP1DAOCALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707639-A1 | CHRYSANTHEMYL DIPHOSPHATE SYNTHASE, CORRESPONDING GENES AND USE IN PYRETHRIN SYNTHESIS | AGRIDYNE TECHNOLOGIES, INC. (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995000634-A1 | CHRYSANTHEMYL DIPHOSPHATE SYNTHASE, CORRESPONDING GENES AND USE IN PYRETHRIN SYNTHESIS | AGRIDYNE TECHNOLOGIES, INC. (US) | 1995-01-05 | — | — | WO | disclosed |