SCHEMBL28599136

SCHEMBL28599136

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Sc1ccc(Cl)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
ALDH1A1 P00352 2/20 0.39
KMT2A Q03164 2/20 0.39
THRB P10828 1/20 0.39
MAPT P10636 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NPC1 O15118 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
CYP2A6 P11509 1/20 0.32
KCNK2 O95069 2/20 0.31
KCNK10 P57789 2/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
MEN1 O00255 1/20 0.31
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28527076 1.00 LMNA (0.39) LMNAALDH1A1KMT2ATHRBMAPT
SCHEMBL28540817 0.98 ALDH1A1 (0.40) LMNAALDH1A1KMT2ATHRBMAPT
SCHEMBL8941503 0.83 LMNA (0.38) LMNAALDH1A1KMT2ATHRBMAPT
SCHEMBL9457748 0.82 ALDH1A1 (0.40) LMNAALDH1A1KMT2ATHRBKDM4E
SCHEMBL30704284 0.80 MAPT (0.34) LMNAALDH1A1KMT2AMAPTNPSR1
SCHEMBL28527062 0.80 LMNA (0.39) LMNAALDH1A1KMT2ATHRBKDM4E
SCHEMBL28580494 0.80 LMNA (0.39) LMNAALDH1A1KMT2ATHRBKDM4E
SCHEMBL9187691 0.80 ALDH1A1 (0.57) LMNAALDH1A1KMT2ATHRBMAPT
SCHEMBL9430594 0.79 ALDH1A1 (0.41) LMNAALDH1A1KMT2ATHRBMAPT
SCHEMBL28535824 0.78 ALDH1A1 (0.40) LMNAALDH1A1KMT2ATHRBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110256623-B Perfluoroalkyl tetrafluorothiomethylene styrene copolymer and application thereof 苏州大学 2021-07-09 CN disclosed