Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28600917 | 0.93 | GRIK1 (0.39) | LMNAKDRMAPTMEN1KMT2A | |
| SCHEMBL28601601 | 0.91 | ALDH1A1 (0.42) | LMNAKDM4EHTTCYP1A2GAA | |
| SCHEMBL28612436 | 0.90 | HTT (0.42) | LMNAKDM4EHTTCYP1A2GAA | |
| SCHEMBL28612707 | 0.88 | MEN1 (0.41) | KDM4EHTTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL28606352 | 0.88 | AR (0.42) | LMNAKDM4EHTTCYP1A2GAA | |
| SCHEMBL28618559 | 0.88 | MEN1 (0.41) | LMNAKDM4EHTTCYP1A2GAA | |
| SCHEMBL28603909 | 0.87 | KDR (0.40) | LMNAKDRMAPTMEN1KMT2A | |
| SCHEMBL28608385 | 0.87 | KDM4E (0.43) | LMNAKDM4EHTTCYP1A2GAA | |
| SCHEMBL28614837 | 0.87 | KDR (0.40) | LMNAKDRMAPTMEN1KMT2A | |
| SCHEMBL28606070 | 0.85 | GRIK1 (0.42) | LMNAKDRMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | claimed |