Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | CCKBR | P32239 | 2/20 | 0.39 |
| ▸ | FPR1 | P21462 | 3/20 | 0.39 |
| ▸ | FPR2 | P25090 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28603909 | 1.00 | KDR (0.40) | KDRCNR1CCKBRFPR1FPR2 | |
| SCHEMBL28919461 | 0.95 | MAOA (0.42) | FPR1FPR2MEN1NPC1LMNA | |
| Aza-Flavanone SCHEMBL28606333 | 0.93 | MAOA (0.45) | CCKBRFPR1FPR2LMNAMAPT | |
| SCHEMBL28606031 | 0.91 | MAPT (0.40) | MEN1NPC1LMNAMAPTCASP3 | |
| SCHEMBL28614923 | 0.91 | GRIK1 (0.40) | KDRCNR1FPR1FPR2MEN1 | |
| SCHEMBL28599139 | 0.91 | GRIK1 (0.40) | KDRCNR1FPR1FPR2MEN1 | |
| SCHEMBL28606070 | 0.90 | GRIK1 (0.42) | KDRCNR1FPR1FPR2MEN1 | |
| SCHEMBL28601605 | 0.90 | KDR (0.39) | KDRFPR1FPR2MEN1NPC1 | |
| SCHEMBL28603992 | 0.90 | KDR (0.39) | KDRFPR1FPR2MEN1NPC1 | |
| SCHEMBL28606032 | 0.90 | GRIK1 (0.41) | KDRCNR1FPR1FPR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | claimed |