Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.55 |
| ▸ | RELA | Q04206 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28501886 | 0.88 | RAB9A (0.50) | KDM4ENFKB1NFKB2RELANPC1 | |
| SCHEMBL2136232 | 0.86 | APP (0.68) | KDM4ENFKB1NFKB2RELANPC1 | |
| SCHEMBL8704440 | 0.85 | KDM4E (0.60) | KDM4ENFKB1NFKB2RELANPC1 | |
| SCHEMBL31145129 | 0.85 | KDM4E (0.60) | KDM4ENFKB1NFKB2RELANPC1 | |
| SCHEMBL4604185 | 0.83 | MAPT (0.76) | KDM4ENFKB1NFKB2RELANPC1 | |
| SCHEMBL12470432 | 0.83 | MAPT (0.61) | KDM4ENFKB1NFKB2RELANPC1 | |
| SCHEMBL24366502 | 0.83 | NPC1 (0.66) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL12470554 | 0.82 | HTT (0.61) | KDM4ENPC1RAB9ADRD4DRD3 | |
| SCHEMBL12470791 | 0.82 | BACE1 (0.53) | KDM4ENFKB1NFKB2RELANPC1 | |
| SCHEMBL30399025 | 0.82 | SMN1; SMN2 (0.49) | KDM4ENFKB1NFKB2RELANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250157-B | Method for synthesizing N- [2- (2-arylbenzothiazole) ] -amide under catalysis of rhodium | 江西师范大学 | 2021-12-21 | — | — | CN | disclosed |
| CN-113105412-A | Method for synthesizing benzothiazole compound | 天津理工大学 | 2021-07-13 | — | — | CN | disclosed |