SCHEMBL2136232

SCHEMBL2136232

Clc1ccc2nc(-c3ccccc3)sc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.68
KDM4E B2RXH2 7/20 0.66
MAPT P10636 7/20 0.66
SMN1; SMN2 Q16637 5/20 0.66
GAA P10253 4/20 0.66
ALDH1A1 P00352 4/20 0.66
GLA P06280 3/20 0.66
MEN1 O00255 3/20 0.66
KMT2A Q03164 3/20 0.66
PKM P14618 2/20 0.66
HPGD P15428 2/20 0.66
LMNA P02545 2/20 0.62
NFKB1 P19838 2/20 0.62
NFKB2 Q00653 2/20 0.62
RELA Q04206 2/20 0.62
CCNE1 P24864 1/20 0.55
CDK2 P24941 1/20 0.55
CDK5 Q00535 1/20 0.55
CDK5R1 Q15078 1/20 0.55
RAB9A P51151 7/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30727497 0.89 APP (0.62) APPKDM4EMAPTSMN1; SMN2GAA
SCHEMBL28599530 0.86 KDM4E (0.57) APPKDM4EMAPTSMN1; SMN2GAA
SCHEMBL3181929 0.85 APP (0.66) APPKDM4EMAPTSMN1; SMN2GAA
SCHEMBL4799750 0.83 APP (0.68) APPKDM4EMAPTSMN1; SMN2GAA
SCHEMBL4593965 0.83 APP (0.94) APPKDM4EMAPTSMN1; SMN2GAA
SCHEMBL12408902 0.82 KDM4E (0.70) APPKDM4EMAPTSMN1; SMN2GAA
SCHEMBL29023857 0.82 SMN1; SMN2 (0.49) APPKDM4EMAPTSMN1; SMN2GAA
SCHEMBL30399025 0.82 SMN1; SMN2 (0.49) APPKDM4EMAPTSMN1; SMN2GAA
SCHEMBL3187010 0.81 KDM4E (0.68) APPKDM4EMAPTSMN1; SMN2GAA
SCHEMBL13853343 0.81 APP (1.00) APPKDM4EMAPTSMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841790-A Method for preparing 2-substituted benzothiazole derivatives by driving light 中国科学院大连化学物理研究所 2025-04-18 CN disclosed
EP-4324831-A1 ARYLAMINE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS Shaanxi Lighte Optoelectronics Material Co., Ltd. (CN) 2024-02-21 EP disclosed
WO-2023123673-A1 NON-AQUEOUS ELECTROLYTE AND LITHIUM-ION BATTERY COMPRISING NON-AQUEOUS ELECTROLYTE 张家港市国泰华荣化工新材料有限公司 2023-07-06 WO disclosed
WO-2023113577-A1 COMPOUNDS AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-06-22 WO disclosed
CN-111793040-B Preparation method of 2-substituted benzothiazole 太原理工大学 2023-01-03 CN disclosed
CN-111793040-A Preparation method of 2-substituted benzothiazole 太原理工大学 2020-10-20 CN disclosed
CN-104910098-B Synthesis method of 2-arylbenzothiazole compound 大连理工大学 2017-03-22 CN disclosed
CN-105884714-A Method for realizing green synthesis of 2-substituted benzothiazole derivatives 内蒙古工业大学 2016-08-24 CN disclosed
CN-103073520-B Method for synthesizing 2-phenyl benzothiazole and derivative thereof HUNAN UNIVERSITY (CN) 2014-10-08 CN disclosed
CN-103073520-A Method for synthesizing 2-phenyl benzothiazole and derivative thereof UNIV HUNAN 2013-05-01 CN disclosed
US-8242278-B2 Process for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-14 US disclosed
US-20120101278-A1 PROCESS FOR PRODUCING BIARYL COMPOUND HAGIYA KOJI (JP) 2012-04-26 US disclosed
EP-1473286-B1 PROCESS FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL CO (JP) 2009-11-04 EP disclosed
US-20090216017-A1 PROCESS FOR PRODUCING BIARYL COMPOUND HAGIYA KOJI 2009-08-27 US disclosed
US-7554000-B2 Process for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-30 US disclosed
CN-1303043-C Process for producing biaryl compound SUMITOMO CHEMICAL CO (JP) 2007-03-07 CN disclosed
CN-1642879-A Process for preparing diaryl compounds SUMITOMO CHEMICAL CO (JP) 2005-07-20 CN disclosed
US-20050096471-A1 Process for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-05-05 US disclosed
EP-1473286-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120101278-A1 PROCESS FOR PRODUCING BIARYL COMPOUND PPOX, CAT, TYR APP 1198/4885KDM4E 3428/4885MAPT 3403/4885
US-20090216017-A1 PROCESS FOR PRODUCING BIARYL COMPOUND PPOX, CAT, TYR APP 1198/4885KDM4E 3428/4885MAPT 3403/4885
US-20050096471-A1 Process for producing biaryl compound PPOX, CAT, TYR APP 1198/4885KDM4E 3428/4885MAPT 3403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.