Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | DHODH | Q02127 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28599674 | 0.85 | NPC1 (0.66) | MAPTDHODHHDAC2MEN1KMT2A | |
| SCHEMBL29512009 | 0.80 | MAPT (0.50) | MAPTDHODHHDAC2AKR1C4AKR1C3 | |
| SCHEMBL11638366 | 0.79 | ALDH1A1 (0.53) | MAPTDHODHMEN1KMT2ANPC1 | |
| SCHEMBL28613064 | 0.79 | HDAC2 (0.57) | MAPTDHODHHDAC2MEN1KMT2A | |
| SCHEMBL7861893 | 0.79 | MAPT (0.69) | MAPTHDAC2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL24252964 | 0.76 | MAPT (0.66) | MAPTHDAC2MEN1KMT2ATP53 | |
| SCHEMBL29434785 | 0.76 | DHODH (0.72) | MAPTDHODHHDAC2AKR1C4AKR1C3 | |
| SCHEMBL15789123 | 0.76 | DHODH (0.72) | MAPTDHODHHDAC2AKR1C4AKR1C3 | |
| SCHEMBL9513479 | 0.76 | MAPT (0.80) | MAPTDHODHAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL2898181 | 0.76 | GAA (0.70) | MAPTMEN1KMT2ATP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200873-B | Ortho-position halogenated arylamine compound and synthesis method thereof | 山东硅科新材料有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-113200873-A | Ortho-position halogenated arylamine compound and synthesis method thereof | 山东硅科新材料有限公司 | 2021-08-03 | — | — | CN | disclosed |