SCHEMBL28599708

SCHEMBL28599708

CC1(O)CCC(NC2CCCCC2)CC1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
HSD17B10 Q99714 1/20 0.55
THRB P10828 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MAPT P10636 2/20 0.36
MGAM O43451 1/20 0.36
SI P14410 1/20 0.36
SIGMAR1 Q99720 2/20 0.35
POLB P06746 1/20 0.35
LMNA P02545 1/20 0.35
EPHX1 P07099 5/20 0.34
CYP3A4 P08684 2/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
ADH1B P00325 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2593362 0.88 ESR2 (0.38) ALDH1A1HSD17B10ESR2
SCHEMBL999618 0.81 ALDH1A1 (0.60) ALDH1A1HSD17B10THRBATML3MBTL1
SCHEMBL26254508 0.80 EPHX2 (0.39) EPHX2ESR2
SCHEMBL26247191 0.77 ALDH1A1 (0.55) ALDH1A1HSD17B10THRBATML3MBTL1
SCHEMBL28146286 0.75 ALDH1A1 (0.75) ALDH1A1HSD17B10THRBATML3MBTL1
Ethane SCHEMBL9776531 0.74 ALDH1A1 (0.86) ALDH1A1HSD17B10THRBATML3MBTL1
SCHEMBL24771540 0.74 ALDH1A1 (1.00) ALDH1A1HSD17B10THRBATML3MBTL1
SCHEMBL25122871 0.74 ALDH1A1 (1.00) ALDH1A1HSD17B10THRBATML3MBTL1
SCHEMBL18657085 0.74 ALDH1A1 (1.00) ALDH1A1HSD17B10THRBATML3MBTL1
SCHEMBL24771539 0.74 ALDH1A1 (1.00) ALDH1A1HSD17B10THRBATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108503555-B 4- ((4- (dimethylamino) cyclohexyl) methyl) cyclohexanol and preparation method and application thereof 万华化学集团股份有限公司 2021-06-29 CN disclosed